Caryophyllene is a terpene that is found in a variety of plants, including cannabis. This terpene has a spicy, woody aroma and is a common flavorant in essential oils. Caryophyllene is also known for its medicinal properties, which include anti-inflammatory and analgesic effects. One of the main ways that this terpene exerts its therapeutic effects is by binding to the CB2 receptor, which is found in the immune system. Research suggests that caryophyllene may be effective in treating conditions like arthritis, Crohn’s disease, and cancer. In addition, this terpene is also believed to help reduce stress and anxiety. When selecting cannabis strains, look for those that contain high levels of caryophyllene if you are seeking relief from pain or inflammation. Strains high in caryophyllene: Granddaddy Purple, OG Kush, Death Star, Girl Scout Cookies.